Sanchez-Ramos, professor of neurology and director of the Huntington’s Disease Center of Excellence at the USF Health Morsani College of Medicine. “This NIH study will allow us to test exactly how the nanoparticles get from the nose to the brain, how they are disseminated from the olfactory bulb to other parts of the brain, and how long they stay before dissipating,” said Dr. Delivering therapeutic molecules for a global brain disease
Sanchez-Ramos comments on the nose-to-brain nanocarrier delivery system his team will be studying and refining.
Not pictured are Neil Aronin, MD, and Anastasia Khvorova, PhD, both of the University of Massachusetts RNA Therapeutics Institute.ĭr. Sanchez-Ramos Vasyl Sava, PhD Xiaoyuan Kong Subhra Mohapatra, PhD Shijiie Song, MD and Shyam Mohapatra, PhD. The interdisciplinary team includes researchers from the USF Department of Neurology, USF Nanomedicine Research Center, Moffitt Cancer Center and the University of Massachusetts Medical School’s RNA Therapeutics Institute.įrom left, the USF team of investigators includes Gary Martinez, PhD (Moffitt Cancer Center) Dr. Sanchez-Ramos and his team - using a mouse model for Huntington’s disease - will assess and refine a new nanoparticle carrier system they’ve designed to transport therapeutic gene-silencing molecules from the nasal passages to the brain. The pledge he made early in his career got a major boost last month when USF Health was awarded a new five-year, $2.3 million grant from the National Institutes of Health’s National Institute of Neurological Disorders and Stroke. They answered with a typical Venezuelan gesture, “¿Y la cura?’” Dr. While celebrating the gene’s discovery with other clinicians in a village, he asked some HD patients gathered why they were not applauding the breakthrough. At the time, he was a clinical team member of the U.S.-Venezuela Collaborative Research Project, a landmark study that identified and documented cases of HD and the disease’s progression in a unique community of families in Lake Maracaibo, Venezuela. When the single lethal gene for HD was discovered in 1993, USF Health neurologist Juan-Sanchez, MD, PhD, promised some patients he would help find a cure or effective treatment for the rare, but ravaging, disease that runs in families. Sanchez-Ramos talk about a major obstacle to gene therapy. Juan Sanchez-Ramos, professor of neurology at the USF Health Morsani College of Medicine, is the lead investigator for a new $2.3-million NIH grant studying a non-invasive drug delivery system designed to safely and effectively transport large therapeutic molecules (nucleic acids) from nose to brain. “This is a site that has routinely been among the top recipients of such notices over the past four years.Dr. “Since 2011, various copyright owners have sent piracy notices on more than 3 million illegal files available through the site,” the RIAA updated last October. Grooveshark was officially shuttered in April of 2015.Īccording to the RIAA, Mp3skull has received more than 3 million DMCA takedown demands since 2011.
That has certainly been the situation surrounding Grooveshark, a site that is still spawning innumerable clones based on its considerable brand recognition and lingering Google search traffic. And that’s a common occurrence following the shutdown of a major piracy brand name. That said, Google results are opening the lane for a myriad of copycats. Earlier, the site - and it’s ever-shifting list of domains - were easily found through a simple Google search, though this appears to be a rare case of ‘take down, stay down’ response the industry is desperately lobbying Congress to enact. Surprisingly, Google has now stripped the domain from its search results, a removal that appears to coincide with the injunction. That site offers downloads from Rihanna, Justin Bieber, Adele, Coldplay, Lil Wayne, Twenty One Pilots, and Fetty Wap readily available. That redirected site is identical to the stripped down directory offered on the. That hopscotch of shifting domain names includes mp3skull.to, mp3skull.cr, mp3skull.is, and mp3skull.yoga, among others.Ĭurrently, the mainstay .com destination remains completely functional, though it is shifting traffic to.
SANCHEZ ONE MILLION MP3 MP3 DOWNLOAD
In a stern decision issued last month by the US District Court for the Southern District of Florida, the illegal mp3 download hub was not only ordered to cease operations immediately, but also cease control of a variety of mp3skull domains.
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